Florida recorded more than 151,000 new cases on Friday, and Hawaii reached 1,167 new infections - both the highest since the start of the pandemic in those states. On Monday, Mississippi recorded 7,839 cases, and Oregon 4,380, which are the highest in the states since the pandemic began.
But of the four states, those with higher vaccination rates - Oregon and Hawaii - have more room left in ICU, suggesting vaccines are reducing severe infections.
Peter Chin-Hong, professor of Medicine at University of California in San Francisco, told CNBC that Oregon and Hawaii were "hurting with explosive case rates, but with high vaccination and masking rates, may not ever be in the same precarious position" as Florida or Mississippi.
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