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AstraZeneca, Under Fire for Vaccine Safety, Released Trial Blueprints

AstraZeneca revealed details of its large coronavirus vaccine trials on Saturday, the third in a wave of rare disclosures by drug companies under pressure to be more transparent about how they are testing products that are the world’s best hope for ending the pandemic.

Polls are finding Americans increasingly wary of accepting a coronavirus vaccine. And scientists inside and outside the government are worried that regulators, pressured by the president for results before Election Day on Nov. 3, might release an unproven or unsafe vaccine.

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UK Prime Minister orders new virus restrictions, could last 6 months

LONDON (AP) — Prime Minister Boris Johnson warned Britons on Tuesday that they should not expect to return to a normal social or work life for at least six months, as he ordered new restrictions that his government hopes will suppress a dramatic surge in confirmed coronavirus cases.

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UK science advisers warn of darker COVID-19 days ahead

LONDON (AP) — Britain’s top medical advisers on Monday painted a grim picture of exponential growth in illness and death if nothing is done to control the second wave of coronavirus infections, laying the groundwork for the government to announce new restrictions later this week.

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OVERVIEW: Virus toll reaches 200,000 in U.S., nearly 1 million worldwide

It is a staggering toll, almost 200,000 people dead from the coronavirus in the United States, and close to one million people around the world.

And the pandemic, which sent cases spiking skyward in many countries and then trending downward after lockdowns, has reached a precarious point. Will countries like the United States see the virus continue to slow? Or is a new surge on the way?

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UPDATE: Moderna and Pfizer Reveal Secret Blueprints for Coronavirus Vaccine Trials

Two drug companies that are leading the race to develop coronavirus vaccines bowed to public pressure on Thursday, abandoning their traditional secrecy and releasing comprehensive road maps of how they are evaluating their vaccines.

The companies, Moderna and Pfizer, revealed details about how participants are being selected and monitored, the conditions under which the trials could be stopped early if there were problems, and the evidence researchers will use to determine whether people who got the vaccines were protected from Covid-19.

Moderna’s study will involve 30,000 participants, and Pfizer’s 44,000.

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As Second Wave of Virus Builds, U.K. Enters New Testing Crisis

LONDON — With Britons fretting last week that a new six-person limit on gatherings would effectively cancel Christmas, Prime Minister Boris Johnson unveiled what he called Operation Moonshot, an audacious plan to test 10 million people every day for the coronavirus and restore life to normal by winter.

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