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Will the COVID-19 crisis trigger a One Health coming-of-age?

https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(20)30179-0/fulltext

As the COVID-19 pandemic continues across the globe, leaving governments and public health services in shock and disarray, calls have been made for the need to adopt One Health approaches to address the failure to predict and halt the emergence of COVID-19.
 
The novel severe acute respiratory syndrome coronavirus 2 is widely suggested to have originated in Asia from a bat reservoir, possibly also involving other animal bridge species. As such, the focus of One Health on the human–animal–environment interface appears particularly compelling.
We concur, however, we warn that conceptual and institutional ambiguities that preclude the practical implementation and evaluation of One Health remain to be resolved.
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How the Aging Immune System Makes Older People Vulnerable to Covid-19

Covid-19 patients who are 80 or older are hundreds of times more likely to die than those under 40.

That’s partly because they are more likely to have underlying conditions — like diabetes and lung disease — that seem to make the body more vulnerable to Covid-19.

But some scientists suggest another likely, if underappreciated, driver of this increased risk: the aging immune system.

The changes that ripple through our network of immune cells as the decades pass are complex, resulting in an overreaction here, a delayed response there and over all, a strangely altered landscape of immunity.

Scientists who study the aging immune system say that understanding it may lead not only to a clearer sense of how age is connected to disease vulnerability, but to better strategies for vaccines and treatments for Covid-19.

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